The nitroreductase enzyme in walker cells that activates 5-(aziridin-1-yl)-2,4-dinitrobenzamide (CB 1954) to 5-(aziridin-1-YL)-4-hydroxylamino-2-nitrobenzamide is a form of NAD(P)H dehydrogenase (quinone) (EC 1.6.99.2)
| Autor: | Knox, Richard J., Boland, Marion P., Friedlos, Frank, Coles, Brian, Southan, Christopher, Roberts, John J. |
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| Zdroj: | In Biochemical Pharmacology 1988 37(24):4671-4677 |
| Databáze: | ScienceDirect |
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