| Autor: |
Jafarpoor Nima, Abbasi-Maleki Saeid, Asadi-Samani Majid, Khayatnouri Mir Hadi |
| Jazyk: |
angličtina |
| Rok vydání: |
2014 |
| Předmět: |
|
| Zdroj: |
Journal of HerbMed Pharmacology, Vol 3, Iss 1, Pp 41-45 (2014) |
| Druh dokumentu: |
article |
| ISSN: |
2345-5004 |
| Popis: |
Introduction: Passiflora incarnata (PI) is one of the commonest herbal anti-anxiety and sedative agents. The aim of the present study was to investigate the antidepressant effect of hydroalcoholic extract of PI in forced swim test (FST) and tail suspension test (TST) in male mice. Methods: In this experimental study, 48 male mice were randomly divided into 6 groups of 8: Negative and positive control groups received normal saline (10 ml/kg), fluoxetine (20 mg/kg) and imipramine (30 mg/kg), respectively and treatment groups received extracts of PI (200, 400 and 800 mg/kg). Immobility, swimming and climbing behaviors were recorded during 6-min. Results: All doses of PI extract compared to control group significantly reduced the duration of immobility time in both of two tests (p |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
|
