Research Advances on Effect of Adipose-derived Stem Cells on Biological Characteristics of Breast Cancer

Autor: WAN Yan, LIANG Zhijie, WEI Changyuan
Jazyk: čínština
Rok vydání: 2019
Předmět:
Zdroj: Zhongliu Fangzhi Yanjiu, Vol 46, Iss 10, Pp 951-955 (2019)
Druh dokumentu: article
ISSN: 1000-8578
DOI: 10.3971/j.issn.1000-8578.2019.19.0429
Popis: Stem cell-assisted transplantation technology has been widely used in superficial soft tissue defect remodeling, and has been the trend of the future in postoperative reconstruction of breast cancer. Adipose-derived stem cells(ADSCs) possess excellent abilities of proliferation, multi-differentiation, paracrine and so on, and they are very important in efficacy optimization of autologous fat grafting. However, ADSCs have been proved to promote the proliferation, epithelialization of breast cancer cells and the formation of new blood vessels in breast cancer in vitro, arousing a controversy about oncology safety. This review aims to outline the potential role of ADSCs in breast reconstruction and discuss their safety impact on breast cancer.
Databáze: Directory of Open Access Journals