Autor: |
Yihong Yang, Rong Zhou, Miaoshan Yuan, Huaiwen He |
Jazyk: |
angličtina |
Rok vydání: |
2023 |
Předmět: |
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Zdroj: |
Micromachines, Vol 14, Iss 10, p 1809 (2023) |
Druh dokumentu: |
article |
ISSN: |
2072-666X |
DOI: |
10.3390/mi14101809 |
Popis: |
Bacterial cellulose (BC) is a green, natural biopolymer with excellent biocompatibility and a film-forming ability. However, its lack of inherent antibacterial activity restricts its application in medical materials and food preservation. In this study, BC derived from the juice of discarded Xinhui citrus was obtained through fermentation and further modified in situ with graphene oxide (GO) to obtain BC(GO). Subsequently, BC(GO) was loaded with cell-compatible polypyrrole (PPy) and antibacterial agent silver nanoparticles (AgNPs) to prepare Ag-PPy/BC(GO) composite films. Composite films were characterized using Fourier-transform infrared spectroscopy (FTIR) and scanning electron microscopy-energy-dispersive X-ray spectroscopy (SEM-EDS) to evaluate their chemical structure and morphology. The results demonstrate effective adsorption of PPy and AgNPs onto the surface of BC nanofibers modified with GO. Antibacterial experiments reveal synergistic antibacterial effects of PPy and AgNPs. The Ag-PPy/BC(GO) membranes exhibit strong antibacterial activity against both Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus), with 48-h growth inhibition rates of 75–84% and 82–84%, respectively. |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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