Proactive esophageal cooling protects against thermal insults during high-power short-duration radiofrequency cardiac ablation

Autor: Marcela Mercado Montoya, Tatiana Gomez Bustamante, Enrique Berjano, Steven R. Mickelsen, James D. Daniels, Pablo Hernandez Arango, Jay Schieber, Erik Kulstad
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: International Journal of Hyperthermia, Vol 39, Iss 1, Pp 1202-1212 (2022)
Druh dokumentu: article
ISSN: 02656736
1464-5157
0265-6736
DOI: 10.1080/02656736.2022.2121860
Popis: Background Proactive cooling with a novel cooling device has been shown to reduce endoscopically identified thermal injury during radiofrequency (RF) ablation for the treatment of atrial fibrillation using medium power settings. We aimed to evaluate the effects of proactive cooling during high-power short-duration (HPSD) ablation.Methods A computer model accounting for the left atrium (1.5 mm thickness) and esophagus including the active cooling device was created. We used the Arrhenius equation to estimate the esophageal thermal damage during 50 W/ 10 s and 90 W/ 4 s RF ablations.Results With proactive esophageal cooling in place, temperatures in the esophageal tissue were significantly reduced from control conditions without cooling, and the resulting percentage of damage to the esophageal wall was reduced around 50%, restricting damage to the epi-esophageal region and consequently sparing the remainder of the esophageal tissue, including the mucosal surface. Lesions in the atrial wall remained transmural despite cooling, and maximum width barely changed (
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