| Autor: |
Raquel M. Melero-Fernandez de Mera, Li-Li Li, Arkadiusz Popinigis, Katryna Cisek, Minna Tuittila, Leena Yadav, Andrius Serva, Michael J. Courtney |
| Jazyk: |
angličtina |
| Rok vydání: |
2017 |
| Předmět: |
|
| Zdroj: |
Nature Communications, Vol 8, Iss 1, Pp 1-18 (2017) |
| Druh dokumentu: |
article |
| ISSN: |
2041-1723 |
| DOI: |
10.1038/ncomms15017 |
| Popis: |
Light-sensitive regulators of protein kinases could offer valuable insights into intracellular signalling. Here the authors design an optogenetic inhibitor of c-Jun N-terminal kinase (JNK) and show evidence for resonance in JNK signalling circuits in neurons, and use the same design principle to develop an inhibitor for p38MAPK. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
|
