| Autor: |
Matteo D′Antonio, Donate Weghorn, Agnieszka D′Antonio-Chronowska, Florence Coulet, Katrina M. Olson, Christopher DeBoever, Frauke Drees, Angelo Arias, Hakan Alakus, Andrea L. Richardson, Richard B. Schwab, Emma K. Farley, Shamil R. Sunyaev, Kelly A Frazer |
| Jazyk: |
angličtina |
| Rok vydání: |
2017 |
| Předmět: |
|
| Zdroj: |
Nature Communications, Vol 8, Iss 1, Pp 1-16 (2017) |
| Druh dokumentu: |
article |
| ISSN: |
2041-1723 |
| DOI: |
10.1038/s41467-017-00100-x |
| Popis: |
Cancer driver mutations can occur within noncoding genomic sequences. Here, the authors develop a statistical approach to identify candidate noncoding driver mutations in DNase I hypersensitive sites in breast cancer and experimentally demonstrate they are regulatory elements of known cancer genes. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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