Multifaceted case management during pregnancy is associated with better child outcomes and less fetal alcohol syndrome
Autor: | Philip A. May, Anna-Susan Marais, Wendy O. Kalberg, Marlene M. de Vries, David Buckley, Julie M. Hasken, Cudore L. Snell, Ronel Barnard Röhrs, Dixie M. Hedrick, Heidre Bezuidenhout, Lise Anthonissen, Erine Bröcker, Luther K. Robinson, Melanie A. Manning, H. Eugene Hoyme, Soraya Seedat, Charles D. H. Parry |
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Jazyk: | angličtina |
Rok vydání: | 2023 |
Předmět: | |
Zdroj: | Annals of Medicine, Vol 55, Iss 1, Pp 926-945 (2023) |
Druh dokumentu: | article |
ISSN: | 07853890 1365-2060 0785-3890 |
DOI: | 10.1080/07853890.2023.2185808 |
Popis: | AbstractBackground Pregnant women participated in multifaceted case management (MCM) to prevent Fetal Alcohol Spectrum Disorders (FASD).Methods Women recruited from antenatal clinics for a longitudinal child development study were screened for alcohol use. Forty-four pregnant women were defined as high-risk drinkers on the Alcohol Use Disorder Identification Test (AUDIT) by an AUDIT score ≥8 and participated in 18 months of MCM to facilitate reduction or cessation of alcohol consumption. Forty-one women completed MCM. Fifty-five equally high-risk women who received standard antenatal care comprised the comparison/control group. Development in offspring was evaluated by a blinded interdisciplinary team of examiners through 5 years of age.Results At five years of age, more children (34%) of MCM participating women did not meet the criteria for FASD vs. non-MCM offspring (22%). Furthermore, a statistically significant (p = .01) lower proportion of MCM offspring (24%) was diagnosed with fetal alcohol syndrome (FAS) compared to controls (49%). Children of MCM participants had significantly (p |
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