Predominant Myofibrillar Pathology with Preserved Sarcolemmal Aquaporin 4 Immunoreactivity in a Patient with Neuromyelitis Optica-Associated HyperCKemia

Autor:	So-Young Huh, Jin-Hong Shin, Yeong-Eun Park, Ho Jin Kim, Dae-Seong Kim
Jazyk:	angličtina
Rok vydání:	2021
Předmět:	anti-aquaporin 4 autoantibody myopathy neuromyelitis optica Medicine (General) R5-920
Zdroj:	Kosin Medical Journal, Vol 36, Iss 2, Pp 206-210 (2021)
Druh dokumentu:	article
ISSN:	2005-9531 2586-7024
DOI:	10.7180/kmj.2021.36.2.206
Popis:	A 49-year-old man developed recurrent myalgia and hyperCKemia during acute attacks of neuromyelitis optica. Muscle biopsy was performed, and the pathological findings were analyzed. Predominant myofibrillar pathology was observed, which constitutes a unique finding that has not been reported before. This case result shows that neuromyelitis optica-associated hyperCKemia can produce variable pathologic phenotypes. Further studies are needed to elucidate the relationship between myofibril destruction and aquaporin 4 autoimmunity.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/fd9b52e06a294b3a8ad5bf1d8b7a5605 Zobrazit plný text záznamu View record in DOAJ