| Autor: |
Chih-Hua Chao, Yuan-Jhong Wu, Tzu-Yin Huang, Chi-Jen Tai, Yi-Ju Chen, Chiung-Yao Huang, Chi-Chien Lin, Chang-Feng Dai, Hui-Chi Huang, Jyh-Horng Sheu |
| Jazyk: |
angličtina |
| Rok vydání: |
2023 |
| Předmět: |
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| Zdroj: |
Molecules, Vol 28, Iss 2, p 641 (2023) |
| Druh dokumentu: |
article |
| ISSN: |
1420-3049 |
| DOI: |
10.3390/molecules28020641 |
| Popis: |
The present chemical investigation on the organic extract of the soft coral Sarcophyton cinereum has contributed to the isolation of four new cembranoids: 16β- and 16α-hydroperoxyisosarcophytoxides (1 and 2), 16β- and 16α-methoxyisosarcophytoxides (3 and 4), and a known cembranoid, lobocrasol (5). The structures of all isolates were elucidated by detailed spectroscopic analysis. Their structures were characterized by a 2,5-dihydrofuran moiety, of which the relative configuration was determined by DU8-based calculation for long-range coupling constants (4JH,H). The cytotoxicity and immunosuppressive activities of all isolates were evaluated in this study. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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