Autor: |
Dhanraj O. Biradar, Yogesh D. Mane, Basi V. Subba Reddy |
Jazyk: |
angličtina |
Rok vydání: |
2022 |
Předmět: |
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Zdroj: |
SynOpen, Vol 06, Iss 04, Pp 312-318 (2022) |
Druh dokumentu: |
article |
ISSN: |
2509-9396 |
DOI: |
10.1055/s-0042-1751381 |
Popis: |
A concise and diastereoselective total synthesis of tetraketide and euscapholide is described in ten steps in 10.6% overall yield from acetaldehyde and (S)-pent-4-ene-1,2-diol. Jacobsen hydrolytic kinetic resolution, Prins cyclization, ring-closing metathesis and oxa-Michael addition reactions are the key steps involved in the synthesis. |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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