Complex mechanisms linking neurocognitive dysfunction to insulin resistance and other metabolic dysfunction [version 2; referees: 2 approved]

Autor: Luke E. Stoeckel, Zoe Arvanitakis, Sam Gandy, Dana Small, C. Ronald Kahn, Alvaro Pascual-Leone, Aaron Pawlyk, Robert Sherwin, Philip Smith
Jazyk: angličtina
Rok vydání: 2016
Předmět:
Zdroj: F1000Research, Vol 5 (2016)
Druh dokumentu: article
ISSN: 2046-1402
DOI: 10.12688/f1000research.8300.2
Popis: Scientific evidence has established several links between metabolic and neurocognitive dysfunction, and epidemiologic evidence has revealed an increased risk of Alzheimer’s disease and vascular dementia in patients with diabetes. In July 2015, the National Institute of Diabetes, Digestive, and Kidney Diseases gathered experts from multiple clinical and scientific disciplines, in a workshop entitled “The Intersection of Metabolic and Neurocognitive Dysfunction”, to clarify the state-of-the-science on the mechanisms linking metabolic dysfunction, and insulin resistance and diabetes in particular, to neurocognitive impairment and dementia. This perspective is intended to serve as a summary of the opinions expressed at this meeting, which focused on identifying gaps and opportunities to advance research in this emerging area with important public health relevance.
Databáze: Directory of Open Access Journals