hepatic manifestation of anorexia nervosa

Autor: Jodi-Anne M. Wallace, Krizia-Ivana T. Udquim, Thomas A. Starnes, Nila S. Radhakrishnan
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: European Journal of Case Reports in Internal Medicine (2023)
Druh dokumentu: article
ISSN: 2284-2594
DOI: 10.12890/2023_003675
Popis: A 30-year-old woman with a history of anorexia nervosa was admitted with weight loss, hypoglycaemia and electrolyte disturbances. During her admission, transaminases peaked at ALP 457 U/l, AST 817 U/l and ALT 1066 U/l. Imaging and laboratory findings were unrevealing, and she declined liver biopsy. Nutrition was introduced via a nasogastric tube and she demonstrated improvement in her laboratory values over several weeks. Her transaminitis was determined to be secondary to severe malnutrition, which has been previously described, but cases with such profound transaminitis are less common. Studies have demonstrated hepatic autophagocytosis as the likely cause.
Databáze: Directory of Open Access Journals