High Postprandial Triglycerides Serum Levels: Is Obesity a Good Predictor?
| Autor: | VIVIANE NOGAROTO, MARCOS R.S. RODRIGUES, MARCELO R. VICARI, MARA C. DE ALMEIDA, FÁBIO Q. MILLÉO, FÁBIO A. DOS SANTOS, ROBERTO F. ARTONI |
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| Jazyk: | angličtina |
| Rok vydání: | 2015 |
| Předmět: | |
| Zdroj: | Anais da Academia Brasileira de Ciências, Vol 87, Iss 1, Pp 437-445 (2015) |
| Druh dokumentu: | article |
| ISSN: | 1678-2690 0001-3765 |
| DOI: | 10.1590/0001-3765201520130380 |
| Popis: | The aim of this study was to analyze the correlation between triglyceride (TG) serum levels in obese and non-obese patients in a simulated postprandial state. Both groups showed TG levels < 150 mg/dL when fasting. After 12 h fasting, the subjects ingested a lipid overload diet and blood samples were collected. The variation between fasting and the postprandial TG peak levels were analyzed. The peak of postprandial TG levels occurred 4 h after the lipid overload in both groups. When the subjects were not fasting, the majority of non-obese subjects remained within the range of normal TG values, but the values for the obese group remained elevated. There was a significant correlation between Body Mass Index (BMI) and TG at each time point until 2 h after the meal, but the data did not show a correlation after 3 h. According to the receiver-operating characteristics (ROC) curve, postprandial TG values were not a good predictor of obesity (based on BMI), but they were a predictor of non-obesity. This study reinforces the importance of measuring non-fasting TG levels in obese and non-obese subjects, because some non-obese patients probably had altered fat metabolism, indicating that this examination could be an indicator of metabolic risk. |
| Databáze: | Directory of Open Access Journals |
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