11β Hydroxylase Deficiency in a Child with Hypothyroidism: A Case Report
Autor: | Bipesh Kumar Shah, Richa Koirala, Sumit Dhamala, Mukesh Bhatta, Shekhar Khatiwada |
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Jazyk: | angličtina |
Rok vydání: | 2023 |
Předmět: | |
Zdroj: | Journal of Nepal Medical Association, Vol 61, Iss 268 (2023) |
Druh dokumentu: | article |
ISSN: | 0028-2715 1815-672X |
DOI: | 10.31729/jnma.8378 |
Popis: | Congenital adrenal hyperplasia occurs due to enzymatic defects in the adrenocortical steroidogenesis. 11β hydroxylase deficiency is the second most common cause of congenital adrenal hyperplasia which presents with hypertension and features of androgen excess. Hypertension has also been found to cause end-organ damage in children with 11β hydroxylase deficiency. We report a case of a 10-year-old male child with hypothyroidism under thyroid replacement therapy, presenting with features of severe hypertension and androgen excess, later on, diagnosed as congenital adrenal hyperplasia due to 11β hydroxylase deficiency. |
Databáze: | Directory of Open Access Journals |
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