Clinical, neuropathological, and molecular characteristics of rapidly progressive dementia with Lewy bodies: a distinct clinicopathological entity?

Autor:	Giuseppe Mario Bentivenga, Simone Baiardi, Andrea Mastrangelo, Edoardo Ruggeri, Angela Mammana, Alice Ticca, Marcello Rossi, Sabina Capellari, Piero Parchi
Jazyk:	angličtina
Rok vydání:	2024
Předmět:	Rapidly progressive dementia Lewy body disease RT-QuIC Alpha-synuclein GBA Seeding amplification assay Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429
Zdroj:	Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-13 (2024)
Druh dokumentu:	article
ISSN:	1758-9193
DOI:	10.1186/s13195-024-01565-x
Popis:	Abstract Background The term rapidly progressive dementia (RPD) with Lewy bodies (rpDLB) is used for DLB patients who develop a rapidly progressive neurological syndrome and have reduced survival. Here, we characterise the clinical, neuropathological, and molecular characteristics of a large rpDLB neuropathological series. Methods We included all RPD patients with a disease duration
Databáze:	Directory of Open Access Journals
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