Mapping of sentinel lymph node drainage using SPECT/CT to tailor elective nodal irradiation in head and neck cancer patients (SUSPECT-2): a single-center prospective trial

Autor:	Pieter D. de Veij Mestdagh, Willem H. Schreuder, Wouter V. Vogel, Maarten L. Donswijk, Eric van Werkhoven, Jacqueline E. van der Wal, Richard Dirven, Baris Karakullukcu, Jan-Jakob Sonke, Michiel W. M. van den Brekel, Corrie A. M. Marijnen, Abrahim Al-Mamgani
Jazyk:	angličtina
Rok vydání:	2019
Předmět:	Head and neck cancer Unilateral elective irradiation Bilateral elective irradiation Lymph drainage mapping Sentinel node Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
Zdroj:	BMC Cancer, Vol 19, Iss 1, Pp 1-9 (2019)
Druh dokumentu:	article
ISSN:	1471-2407
DOI:	10.1186/s12885-019-6331-8
Popis:	Abstract Background The majority of patients with head and neck squamous cell carcinoma (HNSCC) receive bilateral elective nodal irradiation (ENI), in order to reduce the risk of regional failure. Bilateral ENI, as compared to unilateral ENI, is associated with higher incidence of acute and late radiation-induced toxicity with subsequent deterioration of quality of life. Increasing evidence that the incidence of contralateral regional failure (cRF) in lateralized HNSCC is very low (
Databáze:	Directory of Open Access Journals
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