The Potentials of Ergothioneine in the management of diseases in animals
| Autor: | Adakole Adah |
|---|---|
| Jazyk: | English<br />Indonesian |
| Rok vydání: | 2023 |
| Předmět: | |
| Zdroj: | Media Kedokteran Hewan, Vol 34, Iss 1, Pp 36-52 (2023) |
| Druh dokumentu: | article |
| ISSN: | 0215-8930 2775-975X |
| DOI: | 10.20473/mkh.v34i1.2023.36-52 |
| Popis: | The amino acid histidine is the source of the special nutraceutical ergothioneine (ERG), which is a potent antioxidant. Higher plants and animals, who obtain it from the soil and their food, respectively, do not synthesize it; instead, they obtain it through particular microorganisms, such as actinobacteria and mushrooms. Solute carrier family 22, member 4 (SLC22A4), sometimes referred to as organic cation transporter novel type-1 is an incredibly selective transporter for the substance that is only present in animals (OCTN-1). Depending on how OCTN 1 is expressed in different tissues, particularly in those that are more susceptible to oxidative stress, such as erythrocytes, the buildup of ERG differs. ERG concentration is decreased in a number of chronic inflammatory illnesses, and it appears to have potent cytoprotective actions.It has been certified to be relatively safe by regulatory authorities compared to many other antioxidants. |
| Databáze: | Directory of Open Access Journals |
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