STATE REGULATORY T MANAGEMENT OF THE IMMUNE SYSTEM IN PATIENTS WITH KIDNEY CANCER

Autor: Anton Viktorovich Moshev, Vasily Dmitrievich Belenyuk, Ivan Igorevich Gvozdev
Jazyk: English<br />Russian
Rok vydání: 2019
Předmět:
Zdroj: Siberian Journal of Life Sciences and Agriculture, Vol 11, Iss 5, Pp 101-106 (2019)
Druh dokumentu: article
ISSN: 2658-6649
2658-6657
DOI: 10.12731/2658-6649-2019-11-5-101-106
Popis: A study was conducted on the phenotypic composition of peripheral blood T-regulatory cells in patients with kidney cancer. As a result, we found significant changes in the system of adaptive immunity involved in the antitumor immune response. A 17% decrease in the lymphocyte fraction was noted, and a 23% increase in the monocyte population. The detected changes in the T-cell pool may indicate an increase in the ability to migrate into the tissue for the local realization of their functions, as well as an increase in the suppressor function of regulatory T-cells.
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