Subcutaneous interferon β-1a administration by electronic auto-injector is associated with high adherence in patients with relapsing remitting multiple sclerosis in a real-life study

Autor: Elina Järvinen, Juha Multanen, Sari Atula
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Zdroj: Neurology International, Vol 9, Iss 1 (2017)
Druh dokumentu: article
ISSN: 2035-8385
2035-8377
DOI: 10.4081/ni.2017.6957
Popis: The objective was to investigate adherence measured by an electronic auto-injector device, and self-reported adherence and treatment convenience in subjects with relapsing remitting multiple sclerosis (RRMS), using an electronic auto-injector Rebismart® to self-inject interferon β-1a. Thirty one patients with RRMS using the electronic auto-injector Rebismart® for selfinjecting interferon β-1a subcutaneously three times weekly were included in a reallife clinical multicenter study for 24 weeks in Finland. Mean adherence reported by the device and mean self-assessment of adherence were studied. Reasons for missing injections and treatment convenience were assessed. Association between adherence and gender and age were studied. The mean adherence calculated from the device data was 93.5%. The mean self-assessment of adherence was 96.6%. The most common reason for missing an injection was forgetfulness. Adherence (measured by the device) was not changed over time. In the high adherence group there were more females and young patients (
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