Lasia spinosa (L.) thw. attenuates chemically induced behavioral disorders in experimental and computational models

Autor: A.S.M. Ali Reza, Mahfuz Ahmed Sakib, Mst. Samima Nasrin, Jishan Khan, Mohammad Forhad Khan, Md. Amjad Hossen, Md. Hazrat Ali, Md. Anwarul Haque
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Heliyon, Vol 9, Iss 6, Pp e16754- (2023)
Druh dokumentu: article
ISSN: 2405-8440
DOI: 10.1016/j.heliyon.2023.e16754
Popis: Lasia spinosa (L.) Thw. (L. spinosa) is widely used as a folk remedy for different physical ailments, and its neurological effects have yet to be assessed. Phytochemicals status of L. spinosa was evaluated by GC-MS analysis. Membrane stabilization test, elevated plus maze (EPM) tests and hole board tests (HBT), tail suspension tests (TST) and thiopental sodium-induced sleeping tests (TISTT) were used to assess anti-inflammatory, anxiolytic and anti-depressant activity. Fourteen compounds have been recorded from GC-MS analysis. The LSCTF showed 68.66 ± 2.46% hemolysis protections (p
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