COMPARISON OF ORAL DOXYCYCLIN EWITH ORAL MONTELUKAST IN THE TREATMENT OF MODERATE ACNE VULGARIS

Autor: Memoona Aslam, Naeem Raza, Muhammad Nadeem
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Pakistan Armed Forces Medical Journal, Vol 70, Iss 3, Pp 797-800 (2020)
Druh dokumentu: article
ISSN: 0030-9648
2411-8842
Popis: Objective: To compare oral Montelukast with oral Doxycycline in the treatment of moderate Acne Vulgaris in terms of mean change in acne severity index. Study Design: Quasi-experimental study. Place and Duration of Study: Department of Dermatology, Pak Emirates Military Hospital Rawalpindi, from Mar 2016 to Aug 2016. Methodology: A total of 84 patients were included in the study. They were randomly assigned to group A and B by consecutive non probability sampling technique. Group A was given 100mg Doxycycline with topical 10% benzoyl peroxide and group B was given 5mg Montelukast with topical 10% benzoyl peroxide. Acne severity index (ASI) was calculated at base line and after one month. Mean change in acne severity index was observed for both the groups. Results: Independent sample t-test was used to compare the means. Mean post treatment change in acne severity index of group A was 5.45 ± 1.29 and group B was 1.80 ± .59 respectively (p-value
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