| Autor: |
Vânia Maria Sabadoto Brienze, Ângela Pedroso Tonon, Fabrício José Tarelho Pereira, Elisabete Liso, Waldir Antônio Tognola, Manoel Armando Azevedo dos Santos, Marcelo Urbano Ferreira |
| Jazyk: |
angličtina |
| Rok vydání: |
2001 |
| Předmět: |
|
| Zdroj: |
Revista da Sociedade Brasileira de Medicina Tropical, Vol 34, Iss 4, Pp 389-393 (2001) |
| Druh dokumentu: |
article |
| ISSN: |
1678-9849 |
| Popis: |
Two polymerase chain reaction (PCR) protocols showed low sensitivity (36% and 53% for TB AMPLICOR and MPB64 nested PCR, respectively), when compared with classic microbiological methods (73% and 54% for Ziehl-Neelsen staining and culture, respectively), in the diagnosis of tuberculous meningitis in 91 patients in southeastern Brazil. Only three PCR-positive, microbiologically negative patients were found. Analysis of sequential cerebrospinal fluid samples by nested PCR detected Mycobacterium tuberculosis DNA up to 29 days after the introduction of antituberculosis chemotherapy. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
|
