| Autor: |
Mario Saletti, Marco Paolino, Lavinia Ballerini, Germano Giuliani, Gemma Leone, Stefania Lamponi, Marco Andreassi, Claudia Bonechi, Alessandro Donati, Daniele Piovani, Alberto Giacometti Schieroni, Agnese Magnani, Andrea Cappelli |
| Jazyk: |
angličtina |
| Rok vydání: |
2022 |
| Předmět: |
|
| Zdroj: |
Pharmaceutics, Vol 14, Iss 5, p 1041 (2022) |
| Druh dokumentu: |
article |
| ISSN: |
1999-4923 |
| DOI: |
10.3390/pharmaceutics14051041 |
| Popis: |
An easy and viable crosslinking procedure by click-chemistry (click-crosslinking) of hyaluronic acid (HA) was developed. In particular, the clickable propargyl groups of hyaluronane-based HA-FA-Pg graft copolymers showing low and medium molecular weight values were exploited in crosslinking by click-chemistry by using a hexa(ethylene glycol) spacer. The resulting HA-FA-HEG-CL materials showed an apparent lack of in vitro cytotoxic effects, tuneable water affinity, and rheological properties according to the crosslinking degree that suggests their applicability in different biomedical fields. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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