Relationship of lipid metabolism disorders with the development of fatal and non-fatal cardiovascular events in residents of the Chui region of the Kyrgyz Republic of varying sex and ethnicity
| Autor: | A. G. Polupanov, A. U. Mamatov, A. V. Kontsevaya, M. T. Duishenalieva, A. N. Khalmatov, I. Kh. Bebezov, S. M. Akhunbaev, I. S. Sabirov, A. S. Dzhumagulova |
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| Jazyk: | ruština |
| Rok vydání: | 2022 |
| Předmět: | |
| Zdroj: | Кардиоваскулярная терапия и профилактика, Vol 21, Iss 3 (2022) |
| Druh dokumentu: | article |
| ISSN: | 1728-8800 2619-0125 |
| DOI: | 10.15829/1728-8800-2022-3082 |
| Popis: | Aim. To study the relationship of lipid metabolism disorders (overweight, general and abdominal obesity (AO)) with the development of fatal and non-fatal cardiovascular events (CVEs) among residents of the Chui region of the Kyrgyz Republic of varying sex and ethnicity.Material and methods. This study was performed as part of the international prospective epidemiological project “Interepid”. The total follow-up period was 7 years. Vital status at the end of the follow-up period was monitored in 1096 respondents from 1341 initial cohorts. Response rate was 82,1%. As an endpoint, the analysis included cases of fatal and non-fatal CVEs. The prevalence of events was assessed by survival analysis methods (Cox proportional hazard regression model, parametric survival models, Kaplan-Meier estimator).Results. In total, 181 (16,44%) cases of fatal and non-fatal CVEs were recorded during the follow-up period. In individuals with normal body weight, the incidence of CVEs was 10%. In overweight persons, it increased and reached 17,99% (p25 kg/m2 and the presence of AO are independent risk factors for fatal and non-fatal CVEs in the analyzed cohort of residents of the Chui region in women (but not men) of both ethnic groups. |
| Databáze: | Directory of Open Access Journals |
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