The eGVHD App has the potential to improve the accuracy of graft-versus-host disease assessment: a multicenter randomized controlled trial
| Autor: | Helene M. Schoemans, Kathy Goris, Raf Van Durm, Steffen Fieuws, Sabina De Geest, Steven Z. Pavletic, Annie Im, Daniel Wolff, Stephanie J. Lee, Hildegard Greinix, Rafael F. Duarte, Xavier Poiré, Dominik Selleslag, Philippe Lewalle, Tessa Kerre, Carlos Graux, Frédéric Baron, Johan A. Maertens, Fabienne Dobbels |
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| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: | |
| Zdroj: | Haematologica, Vol 103, Iss 10 (2018) |
| Druh dokumentu: | article |
| ISSN: | 0390-6078 1592-8721 |
| DOI: | 10.3324/haematol.2018.190777 |
| Popis: | Graft-versus-host disease (GvHD) assessment has been shown to be a challenge for healthcare professionals, leading to the development of the eGVHD App (www.uzleuven.be/egvhd). In this study, we formally evaluated the accuracy of using the App compared to traditional assessment methods to assess GvHD. Our national multicenter randomized controlled trial involved seven Belgian transplantation centers and 78 healthcare professionals selected using a 2-stage convenience sampling approach between January and April 2017. Using a 1:1 randomization stratified by profession, healthcare professionals were assigned to use either the App (“APP”) or their usual GvHD assessment aids (“No APP”) to assess the diagnosis and severity score of 10 expert-validated clinical vignettes. Our main outcome measure was the difference in accuracy for GvHD severity scoring between both groups. The odds of being correct were 6.14 (95%CI: 2.83–13.34) and 6.29 (95%CI: 4.32–9.15) times higher in favor of the “APP” group for diagnosis and scoring, respectively (P |
| Databáze: | Directory of Open Access Journals |
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