TBR2 coordinates neurogenesis expansion and precise microcircuit organization via Protocadherin 19 in the mammalian cortex

Autor: Xiaohui Lv, Si-Qiang Ren, Xin-Jun Zhang, Zhongfu Shen, Tanay Ghosh, Anjin Xianyu, Peng Gao, Zhizhong Li, Susan Lin, Yang Yu, Qiangqiang Zhang, Matthias Groszer, Song-Hai Shi
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/s41467-019-11854-x
Popis: The T-box protein TBR2 is involved in cortical neurogenesis expansion during neurodevelopment and is preferentially enriched in intermediate progenitors. The authors show that TBR2 coordinates neurogenesis expansion and precise microcircuit assembly in the mouse cortex via PCDH19.
Databáze: Directory of Open Access Journals