Combining fMRI during resting state and an attention bias task in children

Autor: Anita Harrewijn, Rany Abend, Julia Linke, Melissa A. Brotman, Nathan A. Fox, Ellen Leibenluft, Anderson M. Winkler, Daniel S. Pine
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: NeuroImage, Vol 205, Iss , Pp 116301- (2020)
Druh dokumentu: article
ISSN: 1095-9572
DOI: 10.1016/j.neuroimage.2019.116301
Popis: Neuroimaging studies typically focus on either resting state or task-based fMRI data. Prior research has shown that similarity in functional connectivity between rest and cognitive tasks, interpreted as reconfiguration efficiency, is related to task performance and IQ. Here, we extend this approach from adults to children, and from cognitive tasks to a threat-based attention task. The goal of the current study was to examine whether similarity in functional connectivity during rest and an attention bias task relates to threat bias, IQ, anxiety symptoms, and social reticence. fMRI was measured during resting state and during the dot-probe task in 41 children (M = 13.44, SD = 0.70). Functional connectivity during rest and dot-probe was positively correlated, suggesting that functional hierarchies in the brain are stable. Similarity in functional connectivity between rest and the dot-probe task only related to threat bias (puncorr
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