Machine learning of genomic features in organotropic metastases stratifies progression risk of primary tumors

Autor: Biaobin Jiang, Quanhua Mu, Fufang Qiu, Xuefeng Li, Weiqi Xu, Jun Yu, Weilun Fu, Yong Cao, Jiguang Wang
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/s41467-021-27017-w
Popis: The location and timing of metastasis are still fundamentally unpredictable. Here the authors present the Metastatic Network model, a machine learning framework that integrates clinical data and DNA alterations to predict the risk of metastasis to specific organs as well as clinical outcomes
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