Association between lower body temperature and increased tau pathology in cognitively normal older adults

Autor:	Esther M. Blessing, Ankit Parekh, Rebecca A. Betensky, James Babb, Natalie Saba, Ludovic Debure, Andrew W. Varga, Indu Ayappa, David M. Rapoport, Tracy A. Butler, Mony J. de Leon, Thomas Wisniewski, Brian J. Lopresti, Ricardo S. Osorio
Jazyk:	angličtina
Rok vydání:	2022
Předmět:	Tau Phosphorylation Body temperature Aging Alzheimer's disease Neurofibrillary tangle Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571
Zdroj:	Neurobiology of Disease, Vol 171, Iss , Pp 105748- (2022)
Druh dokumentu:	article
ISSN:	1095-953X
DOI:	10.1016/j.nbd.2022.105748
Popis:	Background: Preclinical studies suggest body temperature (Tb) and consequently brain temperature has the potential to bidirectionally interact with tau pathology in Alzheimer's Disease (AD). Tau phosphorylation is substantially increased by a small (
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/dccf07f08d5e400ab5e17b4071c2f542 Zobrazit plný text záznamu Full Text from ScienceDirect View record in DOAJ