Fractional Carbon Dioxide Laser as an 'Add-on' Treatment for Vitiligo: A Meta-analysis with Systematic Review.

Autor: Hyun Jung Kim, Eun Sun Hong, Sang Hyun Cho, Jeong Deuk Lee, Hei Sung Kim
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Zdroj: Acta Dermato-Venereologica, Vol 98, Iss 2, Pp 180-184 (2017)
Druh dokumentu: article
ISSN: 0001-5555
1651-2057
00015555
DOI: 10.2340/00015555-2836
Popis: Treatment of vitiligo is challenging and requires a multidisciplinary approach. Fractional carbon dioxide (CO2) laser as an add-on to conventional treatment has been reported to be effective, but there is no consensus on its use. A systematic review was performed by searching major databases for relevant publications to February 2017. Six studies with 85 participants were included. For those with refractory vitiligo, the addition of fractional CO2 laser to routine treatment modalities was superior to conventional treatment alone in terms of > 50% re-pigmentation (risk ratio (RR) 4.90, 95% confidence interval (95% CI), 1.15–20.93; p = 0.03), physician improvement score (mean difference (MD) 0.81, 95% CI 0.33–1.29; p
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