Deficiency in infiltration of CD8/CD3 positive lymphocytes and macrophages plays a role in lip carcinogenesis: an immunohistochemical study

Autor: Iana Aragão Magalhães, Gabriella Alves Juliao Costa, Marcela Maria Fontes Borges, Anna Clara Aragão Matos Carlos, Karine Cestaro Mesquita, Larissa Mont´Alverne de Arruda, Maria do Perpétuo Socorro Saldanha Cunha, Fabrício Bitu Sousa, Paulo Goberlânio de Barros Silva
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Brazilian Journal of Otorhinolaryngology, Vol 90, Iss 2, Pp 101379- (2024)
Druh dokumentu: article
ISSN: 1808-8694
DOI: 10.1016/j.bjorl.2023.101379
Popis: Objective: To evaluate the immunoexpression profile for CD8, CD3, CD20 and CD68 in the process and carcinogenesis of Carcinoma of the vermilion lip. Methods: Average cell count with positive expression for CD3, CD8, CD20 and CD68. The CD8/CD3 ratio calculated in the region was based on the percentage of positive cells in a total of malignant cells. Kruska-Wallis/Dunn, Mann-Whitney and Spearman correlation tests (SPSS, p
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