Comparative Analysis of Phytochemicals and Antioxidant Characterization Among Different Parts of Catharanthus roseus: In Vitro and In Silico Investigation

Autor: Farjana Akter Hira, Ashekul Islam, Kanika Mitra, Ummey Hafsa Bithi, Khondoker Shahin Ahmed, Sanzida Islam, Shaike Mohammad Abdullah, Md. Nazim Uddin
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Biochemistry Research International, Vol 2024 (2024)
Druh dokumentu: article
ISSN: 2090-2255
DOI: 10.1155/2024/1904029
Popis: Conclusions: The mixed-solvent extract had higher levels of catechin hydrate, rutin hydrate, trans-ferulic acid, and vanillic acid, whereas the ethanol extract contained more (−) epicatechin, catechol, kaempferol, quercetin, and trans-cinnamic acid. While the extracts displayed antioxidant activity, the phytoconstituents also inhibited ROS-generating mPGES-1. These results identify key compounds with potential for developing new chemotherapeutic agents against ROS.
Databáze: Directory of Open Access Journals
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