Preliminary Phytochemical Profile and Bioactivity of Inga jinicuil Schltdl & Cham. ex G. Don
| Autor: | Ammy Joana Gallegos-García, Carlos Ernesto Lobato-García, Manasés González-Cortazar, Maribel Herrera-Ruiz, Alejandro Zamilpa, Patricia Álvarez-Fitz, Ma Dolores Pérez-García, Ricardo López-Rodríguez, Ever A. Ble-González, Eric Jaziel Medrano-Sánchez, Max R. Feldman, Alejandro Bugarin, Abraham Gómez-Rivera |
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| Jazyk: | angličtina |
| Rok vydání: | 2022 |
| Předmět: | |
| Zdroj: | Plants, Vol 11, Iss 6, p 794 (2022) |
| Druh dokumentu: | article |
| ISSN: | 11060794 2223-7747 |
| DOI: | 10.3390/plants11060794 |
| Popis: | Several Mesoamerican cultures have used Inga jinicuil as traditional medicine for the treatment of gastrointestinal, inflammatory, and infectious issues. The aims of this contribution were to elucidate the phytochemical profile of the organic extracts from the bark and leaves of I. jinicuil and to assess the anti-inflammatory and antibacterial properties of these extracts. The preliminary chemical profile was determined by HPLC-PDA and GC-MS; the anti-inflammatory activity was evaluated with a mouse ear edema model, whereas the antibacterial activity was screened against several bacteria. The phytochemical profile of both organs (bark and leaves) of I. jinicuil led to the identification of 42 compounds, such as polyphenolic, flavonoids, triterpenes, prenol-type lipids, and aliphatic and non-aliphatic esters. This molecular diversity gave moderate anti-inflammatory activity (67.3 ± 2.0%, dichloromethane bark extract) and excellent antibacterial activity against Pseudomona aeruginosa and methicillin-resistant Sthaphylococcus aureus (MIC values of ˂3.12 and 50 µg/mL, respectively). These results contribute to the chemotaxonomic characterization and the rational use in traditional medicine of Inga jinicuil Schltdl & Cham. ex G. Don. |
| Databáze: | Directory of Open Access Journals |
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