| Autor: |
Dan Li, Jin Li, Chunlei Li, Qianming Chen, Hong Hua |
| Jazyk: |
angličtina |
| Rok vydání: |
2017 |
| Předmět: |
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| Zdroj: |
Frontiers in Endocrinology, Vol 8 (2017) |
| Druh dokumentu: |
article |
| ISSN: |
1664-2392 |
| DOI: |
10.3389/fendo.2017.00310 |
| Popis: |
BackgroundThe objective of this study was to systemically evaluate the association between oral lichen planus (OLP) and thyroid disease.MethodEleven electronic databases were searched for any clinical study published up until August 2016 that explored an association between OLP and thyroid disease, complemented with manual searching. The titles and abstracts of all studies identified from the electronic searches were then assessed independently to determine inclusion of the study. The population of interest was patients with OLP, and the exposure was the presence of thyroid disease in OLP patients. Statistical analyses were conducted using Review Manager 5.2. The odds ratios (OR) and 95% confidence intervals (CIs) were calculated to evaluate the association between OLP and thyroid disease.ResultsEight studies were included for review, and of these, four case-control studies were included in the final meta-analysis. The mean Newcastle–Ottawa Scale score evaluating the methodological quality of the four studies was 6.5. The OR was 2.10 (95% CI: 1.47–3.01), indicating a statistically significant difference in the prevalence of thyroid disease between the OLP and control groups. Heterogeneity was satisfactory (I2 = 0%, |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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