Autor: |
Nagif Alata Jimenez, Mauricio Castellano, Emilio M. Santillan, Konstantinos Boulias, Agustín Boan, Luisa F. Arias Padilla, Juan I. Fernandino, Eric L. Greer, Juan P. Tosar, Luisa Cochella, Pablo H. Strobl-Mazzulla |
Jazyk: |
angličtina |
Rok vydání: |
2023 |
Předmět: |
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Zdroj: |
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023) |
Druh dokumentu: |
article |
ISSN: |
2041-1723 |
DOI: |
10.1038/s41467-023-37427-7 |
Popis: |
Anti-folate drugs, such as methotrexate, have been largely prohibited for pregnant women because of the teratogenic effect on their descendant. Here, the authors report a intergenerational mechanism by why paternal methotrexate exposure causes craniofacial defects on their offspring. |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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