Outcomes of surgical management of Ebstein anomaly and tricuspid valve dysplasia in critically ill neonates and infantsCentral MessagePerspective

Autor: V. Reed LaSala, MD, Edward Buratto, MD, PhD, Halil Beqaj, MD, Isabel Aguirre, Julian Maldonado, Nimrod Goldshtrom, MD, Andrew Goldstone, MD, PhD, Matan Setton, MD, Ganga Krishnamurthy, MD, Emile Bacha, MD, David M. Kalfa, MD, PhD
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: JTCVS Open, Vol 16, Iss , Pp 629-638 (2023)
Druh dokumentu: article
ISSN: 2666-2736
DOI: 10.1016/j.xjon.2023.08.007
Popis: Objective: To describe the surgical outcomes in neonates and infants who had surgery for Ebstein anomaly (EA) and tricuspid valve dysplasia (TVD). Methods: Retrospective chart review for all patients who underwent surgery for EA or TVD during the index hospitalization after birth at our institution from January 2005 to February 2023. Results: Fifteen symptomatic neonates and infants who had surgery for EA or TVD were included, 8 with EA and 7 with TVD. Eleven patients (73%) and 3 patients (20%) required preoperative inotropes and extracorporeal membrane oxygenation, respectively. Nine patients (60%) had a Starnes procedure and 6 patients (40%) had tricuspid valve repair (TVr). Mortality at last follow-up was 27% overall (n = 4/15), 22% after Starnes (n = 2/9) and 33% after TVr (n = 2/6), without a significant difference despite a greater-risk profile in the Starnes group. Postoperative day 1 lactate level was associated with mortality on Cox regression (hazard ratio, 1.45; P = .01). Three of 9 patients who had a Starnes procedure were or will be converted to a cone repair (1.5/2-ventricle repair). Conclusions: Mortality after surgery for EA or TVD during the index hospitalization after birth is still significant in the current era and is associated with a greater lactate level at postoperative day 1. The Starnes procedure and TVr had comparable outcomes despite a greater-risk profile in the Starnes group. An initial single-ventricle approach does not preclude conversion to biventricular or 1.5-ventricle repair.
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