Neuropsychiatric profile in average intelligent individuals with coexisting epilepsy and psychogenic non‐epileptic seizures

Autor: Alessia Giugno, Iolanda Martino, Ilaria Sammarra, Enrico Fratto, Francesco Fortunato, Angelo Labate, Antonio Gambardella
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Epilepsia Open, Vol 8, Iss 2, Pp 678-684 (2023)
Druh dokumentu: article
ISSN: 2470-9239
DOI: 10.1002/epi4.12731
Popis: Abstract Global neuropsychological impairments with intellectual disability (ID) seem to play a major role in the occurrence of psychogenic non‐epileptic seizures (PNES) in epilepsy. Conversely, the pathophysiology underlying PNES combined with epilepsy without ID remains elusive. We investigated the neuropsychiatric profile in 26 average intelligent subjects (15 women, mean age: 40.04 ± 13.53 years) with temporal lobe epilepsy (TLE) plus PNES (TLE + PNES), compared with 28 with TLE and 22 with PNES alone, matched for age and sex. All subjects underwent neuropsychiatric assessment, including Beck Depression Inventory‐2 (BDI‐2), State‐Trait Anxiety Inventory (STAI), Dissociative Experiences Scale (DES), Toronto Alexithymia Scale (TAS‐20), Traumatic Experience Checklist (TEC), and cognitive evaluation. TLE + PNES and PNES groups shared a similar psychiatric profile with higher levels of depression (BDI‐2, P
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