Indicating and predicting role of the horizontal C/D ratio in preclinical diabetic retinopathy associated with chronic angle-closure glaucoma

Autor: Ze-Long Zhong, Song Chen
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: International Journal of Ophthalmology, Vol 12, Iss 2, Pp 268-274 (2019)
Druh dokumentu: article
ISSN: 2222-3959
2227-4898
DOI: 10.18240/ijo.2019.02.13
Popis: AIM: To observe morphological optic disc characteristics in patients with preclinical diabetic retinopathy (DR) associated with chronic angle-closure glaucoma (CACG). METHODS: Twenty-two cases (43 eyes) of preclinical DR associated with CACG were enrolled in group A; 24 preclinical DR cases (46 eyes) were enrolled in group B; 26 CACG cases (51 eyes) were enrolled in group C; and 49 normal controls (49 eyes) were enrolled in group D. All underwent optical coherence tomography to measure the horizontal C/D ratio (HCDR), C/D area ratio (CDaR), vertical C/D ratio (VCDR), rim area (RA), cup volume (CV), disc area (DA) and average retinal nerve fiber layer (RNFL) thickness. RESULTS: The ages of groups A, B, C, and D were 67.60±3.36, 66.78±3.33, 65.98±3.83, and 67.54±3.17y, respectively. The HCDR values in groups A, B, and C were distinct relative to those in group D (P0.05). The CDaR values in group A were higher in comparison to those in groups B and D (P0.05). The RA values in group A were smaller relative to those in groups B and D (P0.05). The CV values in group A were greater in comparison to those in groups B and D (P0.05). DA was not distinct for comparisons of two groups among the four groups (P>0.05). HCDR value correlated with mean nasal RNFL thickness (r=-0.909, P
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