| Autor: |
Vittorio Pengo, Ricard Cervera, Angela Tincani, Michelle Petri, Jane Salmon, Guillermo Ruiz-Irastorza, Savino Sciascia, Massimo Radin, Paul R Fortin, Pierluigi Meroni, Cecilia Nalli, Maria G Tektonidou, Laura Andreoli, Yu Zuo, Denis Wahl, Medha Barbhaiya, Olga Amengual, Hannah Cohen, Zhuoli Zhang, Guillermo Pons-Estel, Ignasi Rodríguez-Pintó, Rosario Lopez-Pedrera, Maria Gerosa, Bahar Artim-Esen, Maria Laura Bertolaccini, Ann Clarke, Roger Levy, D Ware Branch, LanLan Ji, Giulia Pazzola, Doruk Erkan, Rohan Willis, Jason Knight, Ecem Sevim, Robert Roubey, Michael Belmont, Ian Mackie, Leslie Skeith, Zeynep Belce Erton, Guilherme Ramires de Jesús, Amaia Ugarte, Danieli Andrade, Maria Angeles Aguirre- Zamorano, Michael Lockshin, Emilio Gonzalez, Cecilia B Chighizola, Gustavo Balbi, Stephane Zuily, Maria Efthymiou, Esther Rodgriguez Almaraz, Silvia Foddai, Nina Kello, Jose Pardos-Gea, Flavio Signorelli, Stacy Davis, Zhouli Zhang |
| Jazyk: |
angličtina |
| Rok vydání: |
2022 |
| Předmět: |
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| Zdroj: |
Lupus Science and Medicine, Vol 9, Iss 1 (2022) |
| Druh dokumentu: |
article |
| ISSN: |
2053-8790 |
| DOI: |
10.1136/lupus-2021-000633 |
| Popis: |
Objectives To describe the outcomes of pregnancies in antiphospholipid antibody (aPL)-positive patients since the inception of the AntiPhospholipid Syndrome Alliance for Clinical Trials and InternatiOnal Networking Registry.Methods We identified persistently aPL-positive patients recorded as ‘pregnant’ during prospective follow-up, and defined ‘aPL-related outcome’ as a composite of: (1) Preterm live delivery (PTLD) at or before 37th week due to pre-eclampsia (PEC), eclampsia, small-for-gestational age (SGA) and/or placental insufficiency (PI); or (2) Otherwise unexplained fetal death after the 10th week of gestation. The primary objective was to describe the characteristics of patients with and without aPL-related composite outcomes based on their first observed pregnancies following registry recruitment.Results Of the 55 first pregnancies observed after registry recruitment among nulliparous and multiparous participants, 15 (27%) resulted in early pregnancy loss |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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