| Autor: |
Zeyu Zhang, Madison Pope, Nadia Shakoor, Robert Pless, Todd C. Mockler, Abby Stylianou |
| Jazyk: |
angličtina |
| Rok vydání: |
2022 |
| Předmět: |
|
| Zdroj: |
Frontiers in Artificial Intelligence, Vol 5 (2022) |
| Druh dokumentu: |
article |
| ISSN: |
2624-8212 |
| DOI: |
10.3389/frai.2022.872858 |
| Popis: |
We explore the use of deep convolutional neural networks (CNNs) trained on overhead imagery of biomass sorghum to ascertain the relationship between single nucleotide polymorphisms (SNPs), or groups of related SNPs, and the phenotypes they control. We consider both CNNs trained explicitly on the classification task of predicting whether an image shows a plant with a reference or alternate version of various SNPs as well as CNNs trained to create data-driven features based on learning features so that images from the same plot are more similar than images from different plots, and then using the features this network learns for genetic marker classification. We characterize how efficient both approaches are at predicting the presence or absence of a genetic markers, and visualize what parts of the images are most important for those predictions. We find that the data-driven approaches give somewhat higher prediction performance, but have visualizations that are harder to interpret; and we give suggestions of potential future machine learning research and discuss the possibilities of using this approach to uncover unknown genotype × phenotype relationships. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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