| Autor: |
Ashenafi Kiros Wubshet, Gebremeskel Mamu Werid, Teshale Teklue, Luoyi Zhou, Chimedtseren Bayasgalan, Ariunaa Tserendorj, Jinjin Liu, Livio Heath, Yuefeng Sun, Yaozhong Ding, Wenxiu Wang, Alexei D. Zaberezhny, Yongsheng Liu, Jie Zhang |
| Jazyk: |
angličtina |
| Rok vydání: |
2024 |
| Předmět: |
|
| Zdroj: |
Frontiers in Veterinary Science, Vol 11 (2024) |
| Druh dokumentu: |
article |
| ISSN: |
2297-1769 |
| DOI: |
10.3389/fvets.2024.1360256 |
| Popis: |
BackgroundSeveral factors, such as diverse serotypes, vaccination methods, weak biosecurity, and animal movements, contribute to recurrent Foot-and-Mouth Disease Virus (FMDV) outbreaks in Africa, establishing endemicity. These outbreaks cost over $2 billion annually, prompting a high-priority focus on FMDV vaccination. Despite extensive efforts, vaccine efficacy varies. This study aims to evaluate routine foot and mouth disease (FMD) vaccines in Africa via systematic review and meta-analysis.MethodsA systematic review and meta-analysis were carried out following Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Meta-analysis was conducted to assess the efficacy of FMDV vaccination using the meta for package of R.ResultsVaccinated animals have roughly a 69.3% lower chance of FMDV infection compared to unvaccinated animals, as indicated by the pooled results from the random-effects model, which showed a risk ratio (RR) of 0.3073. There was a statistically significant heterogeneity (p |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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