Separable mixing: The general formulation and a particular example focusing on mask efficiency

Autor: M. C. J. Bootsma, K. M. D. Chan, O. Diekmann, H. Inaba
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Mathematical Biosciences and Engineering, Vol 20, Iss 10, Pp 17661-17671 (2023)
Druh dokumentu: article
ISSN: 1551-0018
DOI: 10.3934/mbe.2023785?viewType=HTML
Popis: The aim of this short note is twofold. First, we formulate the general Kermack-McKendrick epidemic model incorporating static heterogeneity and show how it simplifies to a scalar Renewal Equation (RE) when separable mixing is assumed. A key general feature is that all information about the heterogeneity is encoded in one nonlinear real valued function of a real variable. Next, we specialize the model ingredients so that we can study the efficiency of mask wearing as a non-pharmaceutical intervention to reduce the spread of an infectious disease. Our main result affirms that the best way to protect the population as a whole is to protect yourself. This qualitative insight was recently derived in the context of an SIR network model. Here, we extend the conclusion to proportionate mixing models incorporating a general function describing expected infectiousness as a function of time since infection.
Databáze: Directory of Open Access Journals