Hemophagocytic Lymphohistiocytosis Complicating Dengue and Plasmodium vivax Coinfection

Autor: Muhammad Khurram, Muhammad Faheem, Muhammad Umar, Asif Yasin, Wajeeha Qayyum, Amna Ashraf, Javeria Zahid Khan, Ali Hasnain Yasir, Yusra Ansari, Muhammad Asad, Iram Khan, Shuja Abbas, Irum Rasheed, Natasha Rasool, Hamama Tul Bushra Khar
Jazyk: angličtina
Rok vydání: 2015
Předmět:
Zdroj: Case Reports in Medicine, Vol 2015 (2015)
Druh dokumentu: article
ISSN: 1687-9627
1687-9635
DOI: 10.1155/2015/696842
Popis: Hemophagocytic lymphohistiocytosis (HLH) is a rare disorder. Dysfunction of cytotoxic T and natural killer (NK) cells causes uncontrolled activity of lymphocytes and histiocytes which leads to HLH. Infections, malignancies, and autoimmune disorders are associated with development of HLH. Dengue and Plasmodium vivax are rare causes of HLH. We report the first ever case of a young man who developed fatal HLH that complicated Dengue Hemorrhagic Fever (DHF) and Plasmodium vivax infection.
Databáze: Directory of Open Access Journals