Phenotypic and Molecular-Genetic Analysis of Genetically Modified Toxigenic Vibrio cholerae El Tor Strain 301, Isolated in 2011 in Russia
Autor: | A. V. Shashkova, D. A. Agafonov, A. V. Cherkasov, S. P. Zadnova, N. I. Smirnova |
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Jazyk: | ruština |
Rok vydání: | 2012 |
Předmět: | |
Zdroj: | Проблемы особо опасных инфекций, Vol 0, Iss 4(114), Pp 61-64 (2012) |
Druh dokumentu: | article |
ISSN: | 0370-1069 2658-719X |
DOI: | 10.21055/0370-1069-2012-4-61-64 |
Popis: | The phenotypic and molecular-genetic analysis of Vibrio cholerae O1 El Tor Inaba strain 301, isolated in 2011 from sea water in recreation zone in Taganrog, demonstrated this isolate to be a genetic variant of El Tor cholera causative agent. Its genome was shown to carry a hybrid prophage, containing gene ctxB of classical type and gene rstR of El Tor type, as well as altered pathogenicity island VPI-1 and pandemicity island VSP-II. This strain produced much more cholera toxin (0,12 mcg/ml) than typical strains of this causative agent. |
Databáze: | Directory of Open Access Journals |
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