Can botulinum toxin injection alleviate the pain of bruxism? A Bayesian network analysis and a single-arm analysis

Autor: Ao-bo Zhang, Jian-yun Zhang, Xia Zhou, Li-sha Sun, Tie-jun Li
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Journal of Dental Sciences, Vol 19, Iss 2, Pp 885-893 (2024)
Druh dokumentu: article
ISSN: 1991-7902
DOI: 10.1016/j.jds.2023.08.001
Popis: Background/purpose: There is inconsistent evidence regarding whether the botulinum toxin A (BTA) injection can relieve pain caused by bruxism. This study aimed to estimate the efficiency of BTA injection in relieving pain caused by bruxism at different follow-up periods. Materials and methods: Five electronic databases were searched from 2005 to 2022 using search terms related to botulinum toxin and bruxism. Only controlled clinical trials were included. Two investigators reviewed each article and discussed any disagreements until a consensus was reached. Pain outcomes as evaluated by the visual analogue scale (VAS) were subjected to single-arm and Bayesian network meta-analyses. Pooling data were measured by a random-effects model. Results: Eleven studies with a total of 365 bruxism patients were included. According to the single-arm analyses of the pooled data, the reduction in bruxism-related pain after BTA injection measured 4.06 points (95% CI = 3.37 to 4.75) on the VAS, and the pain relief was significant in the first 6 months after treatment (P
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