Clinical outcome analysis of patients with autism spectrum disorder: analysis from the UK Medical Cannabis Registry
| Autor: | Simon Erridge, Jess Kerr-Gaffney, Carl Holvey, Ross Coomber, Daniela A. Riano Barros, Urmila Bhoskar, Gracia Mwimba, Kavita Praveen, Chris Symeon, Simmi Sachdeva-Mohan, Mikael H. Sodergren, James J. Rucker |
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| Jazyk: | angličtina |
| Rok vydání: | 2022 |
| Předmět: | |
| Zdroj: | Therapeutic Advances in Psychopharmacology, Vol 12 (2022) |
| Druh dokumentu: | article |
| ISSN: | 2045-1261 20451253 |
| DOI: | 10.1177/20451253221116240 |
| Popis: | Introduction: Cannabis-based medicinal products (CBMPs) have been identified as a promising novel therapeutic for symptoms and comorbidities related to autism spectrum disorder (ASD). However, there is a paucity of clinical evidence of their efficacy and safety. Objective: This case series aims to assess changes to health-related quality of life and the incidence of adverse events in patients treated with CBMPs for associated symptoms of ASD enrolled on the UK Medical Cannabis Registry (UKMCR). Methods: Patients treated with CBMPs for ASD-related symptoms for a minimum of 1 month were identified from the UKMCR. Primary outcomes were changes in validated patient-reported outcome measures [Generalised Anxiety Disorder-7 (GAD-7), Single-Item Sleep Quality Scale (SQS), 5-level version of the EQ-5D (EQ-5D-5L) index values] at 1, 3 and 6 months compared with baseline. Adverse events were recorded and analysed. Statistical significance was determined by p |
| Databáze: | Directory of Open Access Journals |
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