| Autor: |
Yasuto Kondo, MD, PhD, Masashi Mikubo, MD, PhD, Masaaki Ichinoe, MD, PhD, Shoko Hayashi, MD, Dai Sonoda, MD, PhD, Masahito Naito, MD, PhD, Yoshio Matsui, MD, PhD, Kazu Shiomi, MD, PhD, Yukitoshi Satoh, MD, PhD |
| Jazyk: |
angličtina |
| Rok vydání: |
2024 |
| Předmět: |
|
| Zdroj: |
Annals of Thoracic Surgery Short Reports, Vol 2, Iss 3, Pp 464-468 (2024) |
| Druh dokumentu: |
article |
| ISSN: |
2772-9931 |
| DOI: |
10.1016/j.atssr.2024.02.009 |
| Popis: |
Background: This study aimed to investigate the diagnostic performance of combined computed tomography (CT) and fluorine-18 fluorodeoxyglucose (FDG) positron emission tomography (PET) for predicting histologic invasiveness of pure ground-glass nodules (pGGNs). Methods: The study analyzed 91 patients who underwent resection of pGGNs and examined the correlation of pathologic invasiveness with preoperative CT and FDG PET findings. Results: Overall, 24, 36, and 31 patients had adenocarcinoma in situ (AIS), minimally invasive adenocarcinoma (MIA), and invasive adenocarcinoma (IAD), respectively. Compared with AIS and MIA, IAD was significantly correlated with larger CT size (P = .001), maximum CT value (P = .026), and high maximum standardized uptake value (SUVmax; P < .001). Multivariable logistic analyses revealed that CT size (odds ratio [OR], 3.848; P = .019) and SUVmax (OR, 4.968; P = .009) were independent predictors of histologic invasiveness. Receiver operating characteristic curve analysis revealed that a cutoff CT size value of 18 mm predicted histologic invasiveness with a sensitivity and specificity of 65% and 80%, respectively; similarly, a cutoff SUVmax value of 1.5 predicted histologic invasiveness with a sensitivity and specificity of 61% and 90%, respectively. Of 20 lesions with CT size ≥18 mm and SUVmax ≥1.5, 16 (80%) were IAD. Of 54 lesions with CT size |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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