Evaluation of mean platelet volume in localized scleroderma
| Autor: | Anil Gulsel Bahali, Ozlem Su, Nazan Emiroglu, Fatma Pelin Cengiz, Mehmet Onur Kaya, Nahide Onsun |
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| Jazyk: | English<br />Portuguese |
| Rok vydání: | 2017 |
| Předmět: | |
| Zdroj: | Anais Brasileiros de Dermatologia, Vol 92, Iss 5, Pp 635-637 (2017) |
| Druh dokumentu: | article |
| ISSN: | 0365-0596 1806-4841 |
| DOI: | 10.1590/abd1806-4841.20176045 |
| Popis: | Abstract: Background: Localized scleroderma is a chronic inflammatory skin disease characterized by sclerosis of the dermis and subcutaneous tissue. Platelets play an important role in inflammation. Following activation, platelets rapidly release numerous mediators and cytokines, which contribute to inflammation. Objectives: To evaluate whether there was any relation between localized scleroderma and platelet parameters. Methods: Forty-one patients with localized scleroderma were enrolled in the study. The control group consisted of 30 healthy subjects. Results: The mean platelet volume level in the patient group was 9.9 ± 1.3 fl and in the control group was 7.6 ± 1.1 fl. This difference was statistically significant (p< 0.001). The plateletcrit values are minimally higher in the patient group as compared to the control group. It was statistically significant (p |
| Databáze: | Directory of Open Access Journals |
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