A Fast, Sensitive and Accurate High Resolution Melting (HRM) Technology-Based Assay to Screen for Common K-ras Mutations
| Autor: | D. Kramer, F. B. Thunnissen, M. I. Gallegos-Ruiz, E. F. Smit, P. E. Postmus, C. J. L. M. Meijer, P.J.F. Snijders, D. A. M. Heideman |
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| Jazyk: | angličtina |
| Rok vydání: | 2009 |
| Předmět: | |
| Zdroj: | Cellular Oncology, Vol 31, Iss 3, Pp 161-167 (2009) |
| Druh dokumentu: | article |
| ISSN: | 1570-5870 1875-8606 |
| DOI: | 10.3233/CLO-2009-0466 |
| Popis: | Background: Increasing evidence points to a negative correlation between K-ras mutations and patient’s response to, or survival benefit after, treatment with EGFR-inhibitors. Therefore, rapid and reliable assays for mutational analysis of the K-ras gene are strongly needed. |
| Databáze: | Directory of Open Access Journals |
| Externí odkaz: |
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